On desktop prototypes, multi-action hotspots can be achieved via multiple designed screens.
Here’s an example that may help illustrate how this would work:
On screen one, you would have your flat designed page. You would add a hover hotspot on an icon that takes you to a second screen. Screen two would have the flat page plus the hotspotted icon window already opened/highlighted.
On mobile prototypes, it's not possible to swipe left/swipe right combination for the same area, thus creating 2 hotspots for one area is not possible at this time.